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SPERMINE
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8
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Nein
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- Spermine biosynthesis in animals starts with decarboxylation of ornithine by the enzyme Ornithine decarboxylase in the presence of PLP.
- Also, spermidine is a precursor to other polyamines, such as spermine and thermospermine, some of which contribute to tolerance against drought and salinity in plants.
- Polyamines such as spermidine and spermine are essential for cellular growth under most conditions, being implicated in many cellular processes including DNA, RNA and protein synthesis.
- It catalyzes the N(1)-acetylation of spermidine and spermine and, by the successive activity of polyamine oxidase, spermine can be converted to spermidine and spermidine to putrescine.
- Agmatinase hydrolyses agmatine to putrescine, the precursor for the biosynthesis of higher polyamines, spermidine and spermine.
- Multivalent organic cations such as spermidine or spermine are also found in cells and these make important contributions to RNA folding.
- Acrolein: elevated levels of acrolein, a toxic metabolite produced from the polyamines spermine, spermidine and by amine oxidase serve as a marker for silent stroke, when elevated in conjunction with C-reactive protein and interleukin 6 the confidence levels in predicting a silent stroke risk increase.
- Streptomyces mutabilis UAE1 has been found to promote plant growth in gray mangroves under greenhouse conditions by producing polyamines putrescine (Put), spermidine (Spd), and spermine (Spm).
- In 2011, a study found that Putrescine (an organic chemical compound) to spermine (an organic chemical compound) canalization has also been found in C.
- The placenta exhibits a unique sex-dependent difference in polyamine metabolism, which is associated with placental-specific escape from X-chromosome inactivation by the enzyme spermine synthase (SMS); moreover, maternal serum levels of polyamine metabolites differ by fetal sex and strongly differentially associate with the great obstetrical syndromes, namely higher maternal serum levels of N1,N12-diacetylspermine (DiAcSpm) increases the risk of pre-eclampsia but decreases the risk of FGR.
- She also used microbial growth as an assay to determine the effectiveness of anti-tumor agents, and examined the role of polyamines such as spermine and spermidine on cell growth.
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