Συνώνυμα & Πληροφορίες σχετικά με | Αγγλικά λέξη OTOTOXICITY

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Παραδείγματα χρήσης OTOTOXICITY σε μια πρόταση

• Ototoxicity is the property of being toxic to the ear (oto-), specifically the cochlea or auditory nerve and sometimes the vestibular system, for example, as a side effect of a drug.
• Food and Drug Administration (FDA) approved sodium thiosulfate under the trade name Pedmark to lessen the risk of ototoxicity and hearing loss in infant, child, and adolescent cancer patients receiving the chemotherapy medication cisplatin.
• Combined with an aminoglycoside, it can increase the possibility of ototoxicity, nephrotoxicity and neuromuscular blockage, result in some hearing loss or can continue to deafness.
• According to the British National Formulary (BNF), netilmicin has similar activity to gentamicin, but less ototoxicity in those needing treatment for longer than 10 days.
• Satraplatin is similar in toxicity profile to carboplatin, with no nephrotoxicity, neurotoxicity, or ototoxicity observed.
• Online pure-tone threshold audiometry (or screening) tests, electrophysiological measures, for example distortion-product otoacoustic emissions (DPOAEs) and speech-in-noise screening tests are becoming increasingly available as a tools to promote awareness and enable accurate early identification of hearing loss across ages, monitor the effects of ototoxicity and/or noise, and guide ear and hearing care decisions and provide support to clinicians.
• Ototoxicity is defined as the toxic effect on the functioning of the inner ear, which may lead to temporary or permanent hearing loss (cochleotoxic) and balancing problems (vestibulotoxic).
• Like zeniplatin and carboplatin, use of enloplatin causes manageable nephrotoxicity, no significant neurotoxicity or ototoxicity, and dose-limiting myelosuppression.

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