Anagrams & Informasjon om | Engelsk ordet AMYLIN

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Eksempler på bruk av AMYLIN i en setning

• Beta cells (β-cells) are specialized endocrine cells located within the pancreatic islets of Langerhans responsible for the production and release of insulin and amylin.
• Amylin plays a role in glycemic regulation by slowing gastric emptying and promoting satiety, thereby preventing post-prandial spikes in blood glucose levels.
• Pramlintide (trade name Symlin) is an injectable amylin analogue drug for diabetes (both type 1 and 2), developed by Amylin Pharmaceuticals (now a wholly owned subsidiary of AstraZeneca).
• Calcitonin gene-related peptide (CGRP) is a member of the calcitonin family of peptides consisting of calcitonin, amylin, adrenomedullin, adrenomedullin 2 (intermedin) and calcitonin‑receptor‑stimulating peptide.
• Preclinical studies have suggested that dual amylin and calcitonin receptor agonists may be more effective than amylin receptor agonists for obesity and type II diabetes.
• Amylin produced three drugs: Symlin (pramlintide acetate), Byetta (exenatide) and Bydureon (exenatide extended release).
• Major firms include Procter & Gamble, headquartered in Cincinnati, Roxane Laboratories, a division of Boehringer Ingelheim, located in Columbus, Forest Pharmaceuticals, a subsidiary of Forest Laboratories, located in Cincinnati, Patheon in Cincinnati, Amylin Pharmaceuticals in West Chester, Auburn Pharmaceuticals in Cleveland, a Sigma-Aldrich facility in Miamisburg, Reese Pharmaceutical in Cleveland, AcelleRX Therapeutics in Cleveland, Akebia Therapeutics in Cincinnati, Kendle International in Cincinnati, Bayer in Newark, Ross Laboratories, a division of Abbott Laboratories, in Columbus, Barr Pharmaceuticals in Cincinnati, and Cardinal Health in Dublin.
• Amylin mimetics that are agonists at the amylin receptors are being developed as therapies for diabetes and obesity, and one, pramlintide, has been FDA approved.

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