Anagrams & Informasjon om | Engelsk ordet AZT

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Eksempler på bruk av AZT i en setning

• Zidovudine (ZDV), also known as azidothymidine (AZT), was the first antiretroviral medication used to prevent and treat HIV/AIDS.
• In 1964, while conducting research for the Michigan Cancer Foundation, Horwitz synthesized a compound that was to become known as zidovudine (AZT) - an antiviral drug used to treat HIV patients; Zidovudine was initially developed as a treatment for cancer.
• On September 14, 1989, seven ACT UP members infiltrated the New York Stock Exchange and chained themselves to the VIP balcony to protest the high price of the only approved AIDS drug, AZT.
• March 20 – The United States Food and Drug Administration for the first time approves an antiretroviral drug for the treatment of HIV/AIDS, zidovudine, also known as AZT (azidothymidine) or Retrovir.
• During his tenure, Young presided over several major agency events, including the Drug Price Competition and Patent Term Restoration Act (1984), passage of the Prescription Drug Marketing Act (1987), approval of the first drug to combat AIDS, zidovudine (AZT) (1987), development of the treatment use of Investigational New Drugs (IND) for the desperately ill, such as people with AIDS, cancer and heart disease (1988); managing the generic drug crisis (1989), during which three officials of the Food and Drug Administration pleaded guilty to receiving bribes, and two manufacturers of generic drugs admitted to providing false data, and the 1989 Chilean grape scare, where Chilean grapes were temporarily banned by the FDA because of a threat and the discovery of two cyanide-tainted grapes.
• It was approved on June 19, 1992, as a monotherapy and again in 1996 for use in combination with zidovudine (AZT).
• Jerome Horwitz of Barbara Ann Karmanos Cancer Institute and Wayne State University School of Medicine synthesizes AZT under a grant from the US National Institutes of Health (NIH).
• is a Japanese virologist famous for his role in discovery of the anti-HIV drug zidovudine (AZT) as well as other anti-AIDS drugs including didanosine (ddI) and zalcitabine (ddC).
• AZT (zidovudine) and other chain-terminating nucleoside analogues used to inhibit HIV-1 reverse transcriptase in the treatment of HIV/AIDS.
• During the first years of the AIDS epidemic, he co-developed zidovudine (AZT), didanosine (ddI), and zalcitabine (ddC), which were the first effective drugs licensed for the treatment of AIDS.
• With his colleagues, he conducted the first clinical trials of zidovudine (AZT), didanosine (ddI), zalcitabine (ddC), and lamivudine (3TC).
• In a 1989 column for Spin, Farber interviewed researchers and doctors who felt AZT, the first approved antiretroviral medication for the treatment of HIV, had been pushed precipitously through the United States Food and Drug Administration approval process owing to political pressures.
• At the time the patent application was filed, Glaxo Wellcome knew that AZT was suitable for prolonged treatment of humans, that compounds of its class could act as chain terminators, and that in vitro efficacy had been shown in human cells.
• Similarly, the mother-to-fetus transmission, and its fetal prophylaxis with antivirals such as tenofovir and AZT, has been evaluated in controlled testing in macaques not possible in humans, and this knowledge has guided antiviral treatment in pregnant mothers with HIV.
• Similarly, the mother-to-fetus transmission, and its fetal prophylaxis with antivirals such as tenofovir and AZT, has been evaluated in controlled testing in macaques not possible in humans, and this knowledge has guided antiviral treatment in pregnant mothers with HIV.
• He performed the first clinical trials in a technique that augments blood cell production in immunodeficient HIV-infected patients and has been a major participant in the development of many AIDS-related therapies including AZT.
• Returning characters include Mary Ann Singleton, who is having difficulty balancing her commitment to her career as a local talk show hostess with her obligations as a wife to Brian and mother to Shawna, the child of her friend Connie, who entrusted the girl's care to Mary Ann on her deathbed; Michael Tolliver, the romantic gay man who has recently tested HIV-positive and is taking AZT to combat the threat to his immune system; and Anna Madrigal, the transgender landlady who mothers her tenants at 28 Barbary Lane on Russian Hill and is fighting to preserve the historic wooden steps of the lane.
• Some of those medicines include: zidovudine (AZT, AIDS), acyclovir (Zovirax, anti-herpes), permethrin (Rid, head and body lice), bupropion (Wellbutrin, antidepressant), colfosceril palmitate (Exosurf, infant acute respiratory distress), remifentanil (Ultiva, analgesic/anesthetic), sumatriptan (Imigran, migraine), salmeterol (Serement, asthma), tacrine (Cognex, Alzheimers), gabapentin (Neurontin, epilepsy and neuropathic pain), troglitazone (Rezulin, diabetes), and atorvastatin (Lipitor, cholesterol lowering).
• John Lauritsen credited Duesberg with cogently explaining the logic of Koch's first postulate and providing a clear explanation of how AZT functions as a "non-selective terminator of DNA synthesis".
• The nucleoside analogs acyclovir (ACV), zidovudine (AZT), didanosine (ddI), zalcitabine (ddC), lamivudine (3TC), stavudine (d4T), trifluridine, didenosine, abacavir, adefovir, and tenofovir has been associated with Fanconi syndrome.
• gendarussa has shown to have a positive activity against several HIV strains, higher than the clinically used first anti-HIV drug, zidovudine AZT.
• Woodroof frequently declares that the drug AZT (azidothymidine) is ineffective and counter-productive, yet years later it is still prescribed to patients with AIDS, albeit at a much lower dose (as mentioned in the epilogue).
• Leibowitch presented to world specialists assembled for the conference at Marnes la Coquette (Pasteur-les Cent Gardes symposium, November 1989) his results showing that the AZT monotherapy becomes quickly ineffective as demonstrated by returning viral levels in the treated patient, though in the first month such levels were significantly, yet only transiently, reduced.
• C-nucleosides isolated from Caribbean Cryptotethya crypta, were the basis for the synthesis of zidovudine (AZT), aciclovir (Cyclovir), cytarabine (Depocyt), and cytarabine derivative gemcitabine (Gemzar).
• During his time as R&D Director, the organisation was responsible for the successful development of Zovirax (anti-herpes); Lamictal (anti-epileptic); Retrovir: AZT (anti-HIVAIDS); Acrivastine (anti-histamine); Atovaquone (PCP/Malaria); Exosurf (infant respiratory distress); Mivacron and Nuromax (neuromuscular blockade); Wellferon (Hepatitis B&C); Zolmitriptan (anti migraine); plus an extensive range of over-the-counter formulations; particularly products for coughs and colds (Sudafed), analgesia (Calpol) and skin care.

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