Synonyme & Informationen zu | Englisch Wort GLIOBLASTOMA

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Beispiele für die Verwendung von GLIOBLASTOMA in einem Satz

• On August 25, 2009, Kennedy died of a brain tumor (glioblastoma) at his home in Hyannis Port, Massachusetts, at the age of 77.
• He was diagnosed with glioblastoma multiforme on 29 August 2002, and wrote about his battle against the cancer on the BBC News website in a series entitled Tumour Diary.
• Glioblastoma, previously known as glioblastoma multiforme (GBM), is the most aggressive and most common type of cancer that originates in the brain, and has a very poor prognosis for survival.
• On July 1, 2013, Daulton underwent surgery for resection of two brain tumors related to glioblastoma at Thomas Jefferson University Hospital in Philadelphia.
• Contributions in the field of genomics include the work of Ludwig researchers at Johns Hopkins to sequence the full complement of genes expressed in many cancers, including head and neck, colon, and breast cancers, as well as glioblastoma multiforme (GBM).
• Etoposide is used as a form of chemotherapy for cancers such as Kaposi’s sarcoma, Ewing's sarcoma, lung cancer, testicular cancer, lymphoma, nonlymphocytic leukemia, and glioblastoma multiforme.
• At present, there are more than 200 clinical trials in progress in the areas like amyotrophic lateral sclerosis, multiple sclerosis, glioblastoma and Huntington's disease.
• On 7 December 1995, Olle collapsed in his Greenwich home due to a brain haemorrhage associated with a previously undiagnosed brain tumour (glioblastoma multiforme) and he was taken to Royal North Shore Hospital, where he underwent neurosurgery the next day.
• Some examples of blastomas are hepatoblastoma, medulloblastoma, nephroblastoma, neuroblastoma, pancreatoblastoma, pleuropulmonary blastoma, retinoblastoma, glioblastoma multiforme and gonadoblastoma.
• Gliomatosis cerebri is most often caused by glioblastoma, but can also arise from astrocytoma, oligodendroglioma or other types of diffuse glioma.
• Carmustine is used as an alkylating agent to treat several types of brain cancer including glioma, glioblastoma multiforme, medulloblastoma and astrocytoma, multiple myeloma, and lymphoma (Hodgkin's and non-Hodgkin).
• In 2015, a phase I clinical trial of PAC-1 opened for enrollment of cancer patients, and in 2016, it was announced that PAC-1 had been granted Orphan Drug Designation for treatment of glioblastoma by the FDA, and in late 2017 a Phase 1b trial began of PAC-1 plus temozolomide for treatment of patients with recurrent glioblastoma or anaplastic astrocytoma.
• Rabadan's work in cancer genomics has led to the identification of driver alterations in hairy cell leukemia, diffuse large B-cell lymphoma, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, splenic marginal zone lymphoma and glioblastoma multiforme; and to the identification of recurrent alterations, which lead to therapy resistance, using longitudinal data in T-cell acute lymphoblastic leukemia.
• He was diagnosed with a Glioblastoma Multiforme IV (GBM 4) brain tumor that was to have killed him in six months.
• In 2016, AstraZeneca completed a phase III trial comparing the efficacy of cediranib alone and cediranib with lomustine to the efficacy of lomustine alone in patients with recurrent glioblastoma.
• When combined with radiation, inhibition of integrin expression by cilengitide synergistically improves the cytotoxic effects of ionizing radiation for glioblastoma.
• Three tumor types were explored during the pilot phase, glioblastoma multiforme (GBM) and high-grade serous ovarian adenocarcinoma, and lung squamous carcinoma.
• These conclusions come from the results of a study that show abnormally high levels of vtRNA expression in cancer cells (derived from glioblastoma, leukemia, and osteocarcinoma cell lines) that had resistance to mitoxantrone.
• Additionally, silencing of GLS and overexpression of GLS2 genes cooperate in decreasing the proliferation and viability of glioblastoma cells.
• Notably, GJA1 expression has been associated with a wide variety of cancers, including nasopharyngeal carcinoma, meningioma, hemangiopericytoma, liver tumor, colon cancer, esophageal cancer, breast cancer, mesothelioma, glioblastoma, lung cancer, adrenocortical tumors, renal cell cancer, cervical carcinoma, ovarian carcinoma, endometrial carcinoma, prostate cancer, thyroid carcinoma, and testicular cancer.
• Mutations in this gene have been found in cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, papillary thyroid carcinoma, non-small-cell lung carcinoma, adenocarcinoma of the lung, brain tumors including glioblastoma and pleomorphic xanthoastrocytoma as well as inflammatory diseases like Erdheim–Chester disease.
• In November 2009, a new, experimental therapeutic approach for treating glioblastoma was published in which the anti-tumor drug Avastin was delivered to the tumor site within the brain through the use of microcatheters, along with mannitol to temporarily open the blood–brain barrier permitting delivery of the chemotherapy into the brain.
• Inhibiting BMI1 has been shown to inhibit the proliferation of glioblastoma multiforme, chemoresistant ovarian cancer, prostatic, pancreatic and skin cancers.
• In addition to neurodegenerative diseases, P4HB level is upregulated in glioblastoma multiforme (GBM) (brain tumor).
• nCD150 isoform was found in tumors of the central nervous system, such as glioblastoma, anaplastic and diffuse astrocytoma and ependymoma.

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