Synonyme & Anagramme | Englisch Wort LBD

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Beispiele für die Verwendung von LBD in einem Satz

• Lewy body dementia (LBD) is an umbrella term for two similar and common subtypes of dementia: dementia with Lewy bodies (DLB) and.
• The GRIA2-encoded AMPA receptor ligand binding core (GluA2 LBD) was the first glutamate receptor ion channel domain to be crystallized.
• In 2007, the French national museum, Centre Georges Pompidou, in Paris acquired LaCie products for its permanent collection including Poulton's "le Coq", "d2"," LBD", "Firewire Speakers", "Pocketdrive" and "Rugged", Ito's "Brick" and "USB Hub", and two Porsche Design drives.
• All subunits have a shared architecture with four domain layers: two extracellular clamshell domains called the N-terminal domain (NTD) and ligand-binding domain (LBD; which binds glutamate), the transmembrane domain (TMD) that forms the ion channel, and an intracellular C-terminal domain (CTD).
• Along with the DBD, the LBD contributes to the dimerization interface of the receptor and in addition, binds coactivator and corepressor proteins.
• Some synthetic retinoid ligands can bind to SHP's LBD and promote its interaction with LXXLL-containing corepressors using the AF-2 site.
• Like Rev-Erbα, Rev-Erbβ has 3 major functional domains which are common to nuclear receptor proteins, including a DNA-binding domain (DBD) and a ligand-binding domain (LBD) at the C-terminus, which are highly conserved in Rev-Erb orthologs, and a N-terminus domain which allows for activity modulation.
• In late 2018, the company announced that while nelotanserin was generally well-tolerated by LBD patients in a small Phase 2 clinical trial for the treatment of REM sleep behavior disorder (RBD) and there were positive indications on some secondary trial outcomes such as sleep diaries and some polysomnogram sleep parameters, the drug failed to meet its primary endpoint of reducing the frequency of RBD episodes and would be discontinued.
• RBD patients however performed better in comprehending novel sentence compared to patients with LBD.

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