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PIAL
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- These consist of endothelial cells and smooth muscle cells, and as these pial arteries further branch and run deeper into the brain, they associate with glial cells, namely astrocytes.
- The upper portion of the fila terminale is formed by spinal pia mater within a dilated dural sac, while the lower portion is formed by both pia and dura mater (with the outer dural layer closely adhering to the inner pial component).
- The neuroepithelial cells span the thickness of the tube's wall, connecting with the pial surface and with the ventricular or lumenal surface.
- Below the medulla spinalis and upper cervical spine, the posterior spinal arteries are rather discontinuous; unlike the anterior spinal artery, which can be traced as a distinct channel throughout its course, the posterior spinal arteries are seen as somewhat larger longitudinal channels of an extensive pial arterial meshwork.
- The anterior optic nerve is supplied by the short posterior ciliary artery and choroidal circulation, while the retrobulbar optic nerve is supplied intraorbitally by a pial plexus, which arises from the ophthalmic artery, internal carotid artery, anterior cerebral artery, and anterior communicating arteries.
- The first patient underwent brain biopsy, which revealed sclerosis of the media and adventitia of small pial and cortical vessels, suggestive of a healed angiitis.
- Disruption of the Gpr56 gene in mice leads to neuronal malformation in the cerebral cortex, which resulted in 4 critical pathological morphologies: defective pial BM, abnormal localized radial glial endfeet, malpositioned Cajal-Retzius cells, and overmigrated neurons.
- The leptomeningeal collateral circulation (also known as leptomeningeal anastomoses or pial collaterals) is a network of small blood vessels in the brain that connects branches of the middle, anterior and posterior cerebral arteries (MCA, ACA, and PCA), with variation in its precise anatomy between individuals.
- These malformations develop in utero by the persistence of fistulae between primitive pia arachnoidal arteries and pial veins that cross each other at right angles.
- Embryologically, the arachnoid trabeculae are the remnants of the common precursor that forms both the arachnoid and pial layers of the meninges.
- In 2015 the milongas of Buenos Aires (El Fulgor de Villa Crespo, Salón Canning, Salón El Pial, Club Sunderland, Club Ciencia y Labor) started arranging monthly competitions whose final culminate in December.
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