Definition & Meaning | English word AEQUORIN
AEQUORIN
Definitions of AEQUORIN
- (biochemistry) A photoprotein, isolated from luminescent jellyfish and other marine organisms, composed of two distinct units: the apoprotein apoaequorin and the prosthetic group coelenterazine.
Number of letters
8
Is palindrome
No
Examples of Using AEQUORIN in a Sentence
- ABC-Transporter Genes - abl gene - acetic acid - acetyl CoA - acetylcholine - acetylcysteine - acid - acidic fibroblast growth factor - acrosin - actin - action potential - activation energy - active site - active transport - adenosine - adenosine diphosphate (ADP) - adenosine monophosphate (AMP) - adenosine triphosphate (ATP) - adenovirus - adrenergic receptor - adrenodoxin - aequorin - aerobic respiration - agonist - alanine - albumin - alcohol - alcoholic fermentation - alicyclic compound - aliphatic compound - alkali - allosteric site - allostery - allotrope - allotropy - alpha adrenergic receptor - alpha helix - alpha-1 adrenergic receptor - alpha-2 adrenergic receptor - alpha-beta T-cell antigen receptor - alpha-fetoprotein - alpha-globulin - alpha-macroglobulin - alpha-MSH - Ames test - amide - amine - amino - amino acid - amino acid receptor - amino acid sequence - amino acid sequence homology - aminobutyric acid - ammonia - AMPA receptor - amyloid - anabolism - anaerobic respiration - analytical chemistry - androgen receptor - angiotensin - angiotensin II - angiotensin receptor - ankyrin - annexin II - antibiotic - antibody - apoenzyme - apolipoprotein - apoptosis - aquaporin - archaea - arginine - argipressin - aromatic amine - aromatic compound - arrestin - Arrhenius equation - aryl hydrocarbon receptor - asparagine - aspartic acid - atom - atomic absorption spectroscopy - atomic mass - atomic mass unit - atomic nucleus - atomic number - atomic orbital - atomic radius - Atomic weight - ATP synthase - ATPase - atrial natriuretic factor - atrial natriuretic factor receptor - Avogadro constant - axon.
- The species is best known as the source of aequorin (a photoprotein), and green fluorescent protein (GFP); two proteins involved in bioluminescence.
- Aequorin is a holoprotein composed of two distinct units, the apoprotein that is called apoaequorin, which has an approximate molecular weight of 21 kDa, and the prosthetic group coelenterazine, the luciferin.
- Calcium concentration microdomains can be visualised with fluorescence microscopy by using aequorin as a reporter protein.
- It is the substrate of many luciferases such as Renilla reniformis luciferase (Rluc), Gaussia luciferase (Gluc), and photoproteins, including aequorin, and obelin.
- For example, the photoprotein aequorin produces a flash of light when luciferin and calcium are added, rather than the prolonged glow that is seen for luciferases when luciferin is added.
- Colocalization of aequorin with GFP facilitates BRET/CRET (Bioluminescence or Chemiluminescence Resonance Energy Transfer), resulting in a 19 - 65 brightness increase.
- victoria, and consists of a 27-kDa green fluorescent protein and the aequorin complex which consists of a 22-kDa apoaequorin, the luminophore coelenterazine, and molecular oxygen.
- Moreover, coelenterazine and its analogs could be applied as prosthetic groups of various photoproteins like mnemiopsin, aequorin, and beroverin.
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