Definition & Meaning | English word AGRANULOCYTOSIS

Definitions of AGRANULOCYTOSIS

1. (disease) An acute condition involving a severe and dangerous leukopenia, particularly of neutrophils, causing a neutropenia in the circulating blood.

Examples of Using AGRANULOCYTOSIS in a Sentence

• Agranulocytosis may be asymptomatic, or may clinically present with sudden fever, rigors and sore throat.
• Metiamide was an effective agent; however, it was associated with unacceptable nephrotoxicity and agranulocytosis.
• Granulocyte deficiency, including decreased numbers of granulocytes (called as granulocytopenia or, if absent, agranulocytosis) such as of neutrophil granulocytes (termed neutropenia).
• However, during these trials, an unacceptable number of patients dosed with metiamide developed agranulocytosis (decreased white blood cell count).
• It is important to monitor any symptoms of fever or sore throat while taking thiamazole; this could indicate the development of agranulocytosis, an uncommon but severe side effect resulting from a drop in the white blood cell count (to be specific, neutropenia, a deficiency of neutrophils).
• Severe adverse reactions are possible, including Steven Johnson syndrome, nephrotoxicity, hepatitis, aplastic anemia, neutropenia, or agranulocytosis.
• Commonly reported adverse effects associated with the use of oxacillin include skin rash, diarrhea, nausea, vomiting, hematuria, agranulocytosis, eosinophilia, leukopenia, neutropenia, thrombocytopenia, hepatotoxicity, acute interstitial nephritis, and fever.
• Adverse effects are uncommon and include skin rashes, pruritus (itching), erythema, angioedema, breathing problems such as dyspnea and asthma, anaphylaxis (serious allergic reactions), and decrease in the number of blood cells such as thrombocytopenia, leucopenia, agranulocytosis, and pancytopenia.
• Patients in this category may be prescribed clozapine, a medication that may be more effective at reducing symptoms of schizophrenia, but treatment may come with a higher risk of several potentially lethal side effects including agranulocytosis and myocarditis.
• Potential risks of levamisole-laced cocaine include neutropenia, agranulocytosis, arthralgias, retiform purpura, skin necrosis, and fever.
• It discussed viral diseases, spirochaetosis and related diseases, bacterial infections such as typhoid fever and tetanus, infections due to acid-fast bacilli including leprosy and tuberculosis, agranulocytosis and kidney diseases.
• The complete list of side effects include: akathisia, contraindication cerebrovascular adverse reactions (including stroke), neuroleptic malignant syndrome, tardive dyskinesia, metabolic changes, hyperglycemia/diabetes mellitus, dyslipidemia, weight gain, orthostatic hypotension, leukopenia, neutropenia, agranulocytosis, seizures, potential for cognitive and motor impairment, difficulties with body temperature regulation, dysphagia, injection site reactions (rash, swelling, redness, irritation at the point of injection), dystonia and pregnancy and nursing complications.

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