Definition, Meaning & Synonyms | English word CHROMAFFIN

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Definitions of CHROMAFFIN

1. (cytology) Having an affinity for (and thus being stained brownish yellow) by chromium salts.

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Examples of Using CHROMAFFIN in a Sentence

• Pheochromocytoma is a rare tumor of the adrenal medulla composed of chromaffin cells and is part of the paraganglioma (PGL) family of tumors, being defined as an intra-adrenal PGL.
• It is the innermost part of the adrenal gland, consisting of chromaffin cells that secrete catecholamines, including epinephrine (adrenaline), norepinephrine (noradrenaline), and a small amount of dopamine, in response to stimulation by sympathetic preganglionic neurons.
• In order to activate chromaffin cells, the splanchnic nerve of the sympathetic nervous system releases acetylcholine, which then binds to nicotinic acetylcholine receptors on the adrenal medulla.
• When a distinction is made, the "aortic bodies" are chemoreceptors which regulate the circulatory system, while the "paraaortic bodies" are the chromaffin cells which manufacture catecholamines.
• Enterochromaffin and enterochromaffin-like cells, both being enteroendocrine cells, are also considered neuroendocrine cells due to their structural and functional similarity to chromaffin cells, although they are not derivatives of the neural crest.
• found that the application of PI-specific phospholipase C into digitonin-permeabilized chromaffin cells decreased PI levels, and inhibited calcium-triggered exocytosis.
• When a distinction is made, the "aortic bodies" are chemoreceptors which regulate circulation, while the "paraaortic bodies" are the chromaffin cells which manufacture catecholamines.
• Enterochromaffin cells are enteroendocrine and neuroendocrine cells with a close similarity to adrenomedullary chromaffin cells secreting serotonin.
• They are essentially of two types: (1) chromaffin or sympathetic paraganglia made of chromaffin cells and (2) nonchromaffin or parasympathetic paraganglia made of glomus cells.
• Another enzyme, AMP-activated protein kinase (AMPK), provides a mechanism that could apply not only to all types of potassium channels but also other oxygen-sensing tissues in the body, such as pulmonary vasculature and neonatal chromaffin cells.
• MIBG is absorbed by and accumulated in granules of adrenal medullary chromaffin cells, as well as in pre-synaptic adrenergic neuron granules.
• Recently, MARCKS has been implicated in the exocytosis of a number of vesicles and granules such as mucin and chromaffin.
• They reported the first direct recordings of quantal neurotransmitter release from brain synapses using an electrochemistry technique known as amperometry, based on the method of Mark Wightman, a chemist at the University of North Carolina, to measure release of adrenaline from adrenal chromaffin cells.
• Initially, FSCV was successfully used for detection of electrochemically active biogenic amines release in chromaffin cells (adrenaline and noradrenaline), brain slices (5-HT, dopamine, norepinephrine) and in vivo in anesthetized or awake and behaving animals (dopamine).
• Secretion of a chromaffin granule protein, chromogranin, from the adrenal gland after splanchnic stimulation.

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