Definition, Meaning & Anagrams | English word HIF

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Definitions of HIF

1. (travel industry) Initialism of higher intermediate fare.
2. Initialism of horizontal integration facility.

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Examples of Using HIF in a Sentence

• Both types of launch vehicles are transported from the HIF to the launch pad aboard a Transporter Erector (TE) which rides on rails up the former crawlerway path.
• When the star player and future national team player Knut Kroon was sold from Stattena to arch-rival HIF, he could barely show up in town.
• Both types of launch vehicles will be transported from the HIF to the launch pad aboard a Transporter Erector (TE) which will ride on rails up the former crawlerway path.
• The buildup of glycolytic metabolites may promote Hypoxia-Inducing Factor (HIF) activation, which creates a feed-forward loop for malignancy progression.
• Global Hearing Health is a new focus of HIF, through its own efforts in humanitarian otology (Neurotology Clinical Fellows spend a rotation on humanitarian worldwide otology) and through a collaboration with Global ENT Outreach.
• Recent genome-wide analysis (GWAS) of HIF binding in kidney cancer showed that HIF1A binds upstream of majorly good prognosis genes, while HIF2A binds upstream to majorly poor prognosis genes.
• A class of prolyl hydroxylases which act specifically on HIF has been identified; hydroxylation of HIF allows the protein to be targeted for degradation.
• MTA1 interacts with ERα and coregulatory factors such as MAT1, MICoA, MTA1 also deacetylate its target proteins such as p53 and HIF and modulates their transactivation functions.
• Prolyl hydroxylation is critical for promoting pVHL binding to HIF, which targets HIF for polyubiquitylation.
• Missense mutations in the active site of these IDH2 induce a neo-enzymatic reaction wherein NADPH reduces αKG to D-2-hydroxyglutarate, which accumulates and leads to the inhibition of hypoxia-inducible factor 1α (HIF1α) degradation (inhibition of the HIF prolyl-hydroxylase), as well as changes in epigenetics and extracellular matrix homeostasis.
• He has played for the Swedish clubs IFK Kristianstad and HIF Karlskrona, polish Wisla Plock and Danish side Skjern Håndbold.
• The HIF warehouse provides hydrologic instruments, equipment, and supplies for USGS as well as Other Federal Agencies (OFA) and USGS Cooperators.
• Ratcliffe found that the VHL protein can bind a hydroxylated residues of HIF when oxygen is present at acceptable levels; the VHL protein then ubiquitylates the HIF protein which ultimately leads to the HIF protein's destruction.

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