Definition, Meaning & Synonyms | English word KISSPEPTIN
KISSPEPTIN
Definitions of KISSPEPTIN
- (protein) A protein-coupled ligand that plays a role in puberty
Number of letters
10
Is palindrome
No
Examples of Using KISSPEPTIN in a Sentence
- Finally, ERĪ± appears to mediate positive feedback effects of estrogen on the brain's secretion of GnRH and LH, by way increasing expression of kisspeptin in neurons of the arcuate nucleus and anteroventral periventricular nucleus.
- The periventricular nucleus has also been shown to have many neurons that express kisspeptin, which generates a surge in LH, which ultimately leads to the release of GnRH.
- This research led to the discovery that kisspeptin stimulates the neurons that were involved in the release of gonadotropin-releasing hormone (GnRH) and possibly may have some impact on the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
- Reproductive function is highly dependent on levels of both neurokinin B and also the G-protein coupled receptor ligand kisspeptin.
- Mutations in the kisspeptin receptor KISS1R have resulted in isolated hypogonadotropic hypogonadism (IHH), characterized by delayed or absence of puberty.
- Kisspeptin, neurokinin B, and dynorphin (KNDy) neurons are neurons in the hypothalamus of the brain that are central to the hormonal control of reproduction.
- This neurohormone also acts on the hypothalamus to inhibit the expression of GnRH, which may further inhibit gonadotropin secretion, and kisspeptin, which may inhibit kisspeptin-mediated stimulation of GnRH neurons prior to the preovulatory hormonal surge.
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