Definition, Meaning & Synonyms | English word PALMITOYLETHANOLAMIDE

Definitions of PALMITOYLETHANOLAMIDE

1. (biochemistry) An endogenous fatty acid amide, belonging to the class of nuclear factor agonists, with anti-inflammatory, antinociceptive, neuroprotective and anticonvulsant properties.

Examples of Using PALMITOYLETHANOLAMIDE in a Sentence

• During this period, more insight into the functions of endogenous fatty acid derivatives emerged, and compounds such as oleamide, palmitoylethanolamide, 2-lineoylglycerol and 2-palmitoylglycerol were explored for their capacity to modulate pain sensitivity and inflammation via what at that time was thought to be the endocannabinoid signalling pathway.
• Some ethanolamides are naturally occurring, such as anandamide, palmitoylethanolamide and prostamides, which play physiological roles as lipid neurotransmitters and autacoids.
• NaGly is an endogenous inhibitor of fatty acid amide hydrolase (FAAH) and thereby increases the ethanolamide endocannabinoids AEA, oleoylethanolamide (OEA) and palmitoylethanolamide (PEA) levels.

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