Synonyymit & Tietoja | englanti sana TRANSAMINASE
TRANSAMINASE
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- Serum ALT level, serum AST (aspartate transaminase) level, and their ratio (AST/ALT ratio) are routinely measured clinically as biomarkers for liver health.
- Serum AST level, serum ALT (alanine transaminase) level, and their ratio (AST/ALT ratio) are commonly measured clinically as biomarkers for liver health.
- The transaminase alanine: glyoxylate aminotransferase 1 (AGT1) has been shown to be crucial to the pathogenicity of M.
- Laboratory results include higher plasma/serum transaminase activity, hyperammonemia, acidosis, hypoglycemia, and an increased anion gap.
- The most common side effects include infection, febrile neutropenia, decreased appetite, hyperglycemia, mucositis, hypoxia, hemorrhage, increased transaminase, diarrhea, nausea, and hypotension.
- Alanine aminotransaminase (ALT), also known as Glutamic-pyruvic transaminase (GPT), then coverts glutamate back into α-ketoglutarate, this time transferring the ammonium to pyruvate resulting from glycolysis, forming free alanine.
- Liver injury: elevated serum glutamic oxaloacetic transaminase (SGOT) (also known as aspartate transaminase, AST) and lactic acid dehydrogenase (LDH).
- Enzymes utilizing such cofactors include the PLP-dependent enzyme aspartate transaminase and the TPP-dependent enzyme pyruvate dehydrogenase.
- Alanine aminotransferase and aspartate transaminase are usually suggestive of liver disease whereas elevation of bilirubin and alkaline phosphatase suggests common bile duct obstruction.
- Platelet count, aspartate transaminase, alanine transaminase, and haptoglobin are usually unaffected and may be used to distinguish mirror syndrome from HELLP syndrome.
- In a similar mechanism of aspartate transaminase, the lysine that forms the initial imine to PLP later acts as the base that attacks the tyrosine in transimination.
- It is formed from GABA by the action of GABA transaminase (4-aminobutyrate aminotransferase) and further oxidised to become succinic acid, which enters TCA cycle.
- Other names in common use include dialkyl amino acid (pyruvate) decarboxylase, alpha-dialkyl amino acid transaminase, 2,2-dialkyl-2-amino acid-pyruvate aminotransferase, L-alanine-alpha-ketobutyrate aminotransferase, dialkylamino-acid decarboxylase (pyruvate), and 2,2-dialkylglycine carboxy-lyase (amino-transferring).
- Other names in common use include norleucine transaminase, norleucine (leucine) aminotransferase, and leucine L-norleucine: 2-oxoglutarate aminotransferase.
- Other names in common use include alanine-oxomalonate aminotransferase, L-alanine-ketomalonate transaminase, and alanine-ketomalonate (mesoxalate) transaminase.
- Other names in common use include prephenate transaminase (ambiguous), PAT (ambiguous), prephenate aspartate aminotransferase, and L-aspartate:prephenate aminotransferase.
- Other names in common use include amine transaminase, amine-ketoacid transaminase, diamine aminotransferase, and diamine-ketoglutaric transaminase.
- Other names in common use include dopa transaminase, dihydroxyphenylalanine aminotransferase, aspartate-DOPP transaminase (ADT), L-dopa transaminase, dopa aminotransferase, glutamate-DOPP transaminase (GDT), phenylalanine-DOPP transaminase (PDT), DOPA 2-oxoglutarate aminotransferase, and DOPAATS.
- Other names in common use include diiodotyrosine aminotransferase, halogenated tyrosine aminotransferase, and halogenated tyrosine transaminase.
- Other names in common use include prephenate transaminase (ambiguous), PAT (ambiguous), and L-glutamate:prephenate aminotransferase.
- Other names in common use include imidazolylacetolphosphate transaminase, glutamic-imidazoleacetol phosphate transaminase, histidinol phosphate aminotransferase, imidazoleacetol phosphate transaminase, L-histidinol phosphate aminotransferase, histidine:imidazoleacetol phosphate transaminase, IAP transaminase, and imidazolylacetolphosphate aminotransferase.
- Other names in common use include kynurenine transaminase (cyclizing), kynurenine 2-oxoglutarate transaminase, kynurenine aminotransferase, and -kynurenine aminotransferase.
- The systematic name of this enzyme class is nicotianamine:2-oxoglutarate aminotransferase; nicotianamine transaminase.
- Other names in common use include pyridoxamine phosphate aminotransferase, pyridoxamine 5'-phosphate-alpha-ketoglutarate transaminase, and pyridoxamine 5'-phosphate transaminase.
- Other names in common use include L-phenylalanine-2-oxoglutarate aminotransferase, tryptophan aminotransferase, 5-hydroxytryptophan-ketoglutaric transaminase, hydroxytryptophan aminotransferase, L-tryptophan aminotransferase, and L-tryptophan transaminase.
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