Anagrammes & Informations sur | Mot Anglaise ICOS

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Exemples d’utilisation de ICOS dans une phrase

• Icos is best known for the development of tadalafil (Cialis), a drug used to treat erectile dysfunction.
• Mostly studied are those belonging to Immunoglobulin super-family (IgSF) (such as CD28, B7, ICOS, CD226 or CRTAM) and TNF receptor super-family (TNFRSF) (such as 41-BB, OX40, CD27, GITR, HVEM, CD40, BAFFR, BAFF and others).
• The opposing roles of CD28 and ICOS compared to CTLA4 cause that these receptors act as a rheostat for the immune response through competitive pro- and anti-inflammatory effects.
• Inducible T-cell costimulator (also called CD278) is an immune checkpoint protein that in humans is encoded by the ICOS (Inducible T-cell COStimulator) gene.
• In addition, blockade of ICOS/ICOSLG interaction in animal models of experimental allergic encephalomyelitis and of cardiac allograft rejection revealed a critical role of ICOS and its ligand in inflammatory immune reactions.
• She was formerly President and Founder of The International Council on Security and Development (ICOS), an international security and development think tank founded in 2002 with offices in Kabul, London, Rio de Janeiro, Brussels and Paris, and field offices in the Afghan cities of Lashkar Gah and Kandahar City.

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