Definition, Meaning & Anagrams | English word TREG
TREG
Definitions of TREG
- A regulatory T cell: a kind of T cell that modulates the immune system.
Number of letters
4
Is palindrome
No
Examples of Using TREG in a Sentence
- In addition to that, it has been found that dendritic cell (DC) - Treg interaction causes sequestration of Fascin-1, an actin-bundling protein essential for immunological synapse formation and skews Fascin-1–dependent actin polarization in antigen presenting DCs toward the Treg cell adhesion zone.
- For instance, some non-naive T cells express surface markers similar to naive T cells (Tscm, stem cell memory T cells; Tmp, memory T cells with a naive phenotype), some antigen-naive T cells have lost their naive phenotype, and some T cells are incorporated within the naive T cell phenotype but are a different T cell subset (Treg, regulatory T cells; RTE, Recent Thymic emigrant).
- Treg expression of CTLA-4 can effectively downregulate both CD80 and CD86 on APCs, suppress the immune response and lead to increased anergy.
- HLA-G is inducer of Treg, MDSC, polarise macrophages into alternatively activated M2 and has other immunosuppressive effects on immune cells.
- Notably, it has also been observed on a subpopulation of natural Treg (nTreg) cells with high expression levels of PD-1, which had impaired IL-2 responsiveness, and also on Helios Treg cells, where it was co-expressed with T-cell immunoreceptor with Ig and ITIM domains (TIGIT).
- Glycols typically seen in industry include triethylene glycol (TEG), diethylene glycol (DEG), ethylene glycol (MEG), and tetraethylene glycol (TREG).
- Moreover, the loss of suppressive phenotype of Treg cells was observed in tumors, but not in splenic Tregs, which can potentially have great clinical significance.
- GITR can be used as Treg marker and its signaling abrogates the suppressive function of regulatory T cells.
- Through cAMP signaling, CyaA also alters TLR-triggered maturation of dendritic cells, inhibiting proinflammatory IL-12 and TNF-α secretion and enhancing IL-10 production and Treg expansion, preventing the induction of adaptive immune responses to Bordetella infections.
- Superstar Treg Lee leads the Vikings to a 65-58 victory in the finals over Meadville, a team that would make it all the way to the PA State AAAA championship game.
- Upon returning to the University of Oxford in 1996, first to the Nuffield Department of Surgery and later, the Sir William Dunn School of Pathology, Powrie used the T cell transfer model to identify the suppressive mechanisms used by regulatory T cells to prevent intestinal inflammation including the requirements for CTLA-4 and the capacity of Treg to prevent colitis driven by innate immune cells as well as CD4+ T cells.
- Because the predominant features of the disease include autoantibody-mediated disease (AIHA, ITP), Treg defects (resembling those found in CTLA4 haploinsufficient patients), autoimmune infiltration (of non-lymphoid organs, also resembling that found in CTLA4 haploinsufficient patients), and enteropathy, the disease has been termed LATAIE for LRBA deficiency with autoantibodies, Treg defects, autoimmune infiltration, and enteropathy.
- Foxp3 Treg development is supported by mTECs during negative selection, when thymocytes have TCR specificities with intermediate affinity for self antigens.
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