Informations sur | Mot Anglaise HOLIN

Exemples d’utilisation de HOLIN dans une phrase

• Mature virons are released by lysis, which, in the case of PRD1, is achieved with the aid of virus-encoded lysis machinery consisting of four proteins: P15 (endolysin), P35 (holin), P36 and P37 (homologues of the Rz/Rz1 proteins of phage lambda).
• As in holin superfamily I, proteins in these families generally exhibit of 2 transmembrane spanners (TMSs).
• Expression of holin S at a precisely scheduled time after phage infection terminates respiration and allows release of a muralytic enzyme, endolysin, that hydrolyzes the cell wall.
• Although the endolysin of phage T4 encoded by the e gene (Lysozyme E) was identified in 1961, the holin (product of gene t and called T-holin) was not characterized until 2001.
• CidA, a 131 aa protein with 4 putative TMSs, is believed to be the holin which exports the autolysin CidB, while LrgA may be an anti-holin, a protein that binds and inhibits holin activity.

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